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Invitrogen
ST8SIA2 Polyclonal Antibody
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ST8SIA2 Antibody (PA5-96787) in WB
Western blot analysis of ST8SIA2 in extracts of various cell lines. Samples were incubated with ST8SIA2 Polyclonal antibody (Product # PA5-96787) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-96787
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 24-160 of human ST8SIA2 (NP_0060021)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.15 mg/mL
规格
115 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DISEIEEEIG NSGGRGTIRS AVNSLHSKSN RAEVVINGSS SPAVVDRSNE SIKHNIQPAS SKWRHNQTLS LRIRKQILKF LDAEKDISVL KGTLKPGDII HYIFDRDSTM NVSQNLYELL PRTSPLKNKH FGTCAIV; Positive Samples: THP-1, SKOV3, Mouse testis, Mouse brain, Mouse heart, Mouse lung, Rat brain, Rat heart; Cellular Location: Golgi apparatus membrane, Single-pass type II membrane protein
靶标信息
The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha-2,8-sialyltransferase 8B 1; developmentally regulated member of sialyltransferase gene family; MGC116854; MGC116857; polysialic acid synthase; polysialyltransferase; sialyltransferase 8 (alpha-2, 8-sialyltransferase) B; sialyltransferase 8 (alpha-2, 8-sialytransferase) B; sialyltransferase 8B; sialyltransferase St8Sia II; sialyltransferase X; sialytransferase St8Sia II; SIAT8-B; ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 2; ST8Sia II; ST8SiaII; unnamed protein product
基因别名: HsT19690; SIAT8-B; SIAT8B; ST8SIA-II; ST8SiaII; STX
UniProt ID: (Human) Q92186, (Mouse) O35696, (Rat) Q07977
Entrez Gene ID: (Human) 8128, (Mouse) 20450, (Rat) 117523
ganglioside biosynthetic process
N-glycan processing
glycoprotein biosynthetic process
oligosaccharide metabolic process
neuron differentiation
response to cocaine
positive regulation of neuron apoptotic process
positive regulation of synapse assembly
sialylation
neuron projection extension
carbohydrate metabolic process
nervous system development
protein modification process
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