Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:200-1:1,000 | - |
免疫组化(石蜡) (IHC (P)) |
1:25-1:100 | - |
产品规格 | |
---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Fusion protein corresponding to residues near the C terminal of human stromal antigen 2 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.9 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2636236 |
The antibody detects endogenous levels of total Stromal antigen 2 / STAG2 protein.
STAG2 is a component of the cohesin complex. This complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cohesin subunit SA-2; DKFZp686P168; DKFZp781H1753; FLJ25871; OTTHUMP00000024338; OTTHUMP00000043514; OTTHUMP00000043515; OTTHUMP00000081754; OTTHUMP00000081755; RP11-517O1.1; SCC3 homolog 2; Stromal antigen 2
基因别名: bA517O1.1; SA-2; SA2; SCC3B; STAG2
UniProt ID: (Human) Q8N3U4
Entrez Gene ID: (Human) 10735
分子生物学功能:
chromatin/chromatin-binding, or -regulatory protein