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This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants.
Protein Aliases: Breast tumor kinase substrate; brk kinase substrate; BRK substrate; FLJ20234; Signal-transducing adaptor protein 2; signal-transducing adaptor protein-2; STAP-2
Gene Aliases: BKS; STAP2
UniProt ID: (Human) Q9UGK3
Entrez Gene ID: (Human) 55620
Molecular Function: scaffold/adaptor protein