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Invitrogen
STAT6 Polyclonal Antibody
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产品信息
PA1-23018
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Syn. Pep. of STAT6 region in exons 16 and 17 of human ortholog (LocusLinkID 6778) (conserved in Ms)
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
4°C, do not freeze
运输条件
Wet ice
产品详细信息
PA1-23018 detects STAT6 Rabbit in Human and Mouse samples.
PA1-23018 has been successfully used in Immunocytochemistry, Immunohistochemistry, Immunoprecipitation and Western Blot procedures.
PA1-23018 immunogen corresponds to Syn. Pep. of STAT6 region in exons 16 and 17 of human ortholog (LocusLinkID 6778) (conserved in Ms).
靶标信息
STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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