FIGURE: 1 / 2
Peptide Sequence: LGYKASTNLQ DQLEKTGENK GWSGPKPGFP EPTNNTPKGI LHLSPDVYQE MEASRHKVIS GTTLGYLSPK DMNQPSSSFF SISPTSNSSA TIARELLMNG
Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48. 5% and 59. 9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene.
Protein Aliases: Double-stranded RNA-binding protein Staufen homolog 2; staufen homolog 2; staufen, RNA binding protein, homolog 2
Gene Aliases: 39K2; 39K3; STAU2
UniProt ID: (Human) Q9NUL3
Entrez Gene ID: (Human) 27067