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Proteintech
STK11 Monoclonal Antibody (1H8E4)
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产品信息
66719-1-IG
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1H8E4
抗原
STK11 Fusion Protein Ag13436 (133-433 aa encoded by BC007981)
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: VCGMQEMLD SVPEKRFPVC QAHGYFCQLI DGLEYLHSQG IVHKDIKPGN LLLTTGGTLK ISDLGVAEAL HPFAADDTCR TSQGSPAFQP PEIANGLDTF SGFKVDIWSA GVTLYNITTG LYPFEGDNIY KLFENIGKGS YAIPGDCGPP LSDLLKGMLE YEPAKRFSIR QIRQHSWFRK KHPPAEAPVP IPPSPDTKDR WRSMTVVPYL EDLHGADEDE DLFDIEDDII YTQDFTVPGQ VPEEEASHNG QRRGLPKAVC MNGTEAAQLS TKSRAEGRAP NPARKACSAS SKIRRLSACK QQ (133-433 aa encoded by BC007981)
靶标信息
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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