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Proteintech
STOML1 Polyclonal Antibody
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产品信息
12862-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
STOML1 Fusion Protein Ag3978 (79-398 aa encoded by BC034379)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LKIVPTYER MIVFRLGRIR TPQGPGMVLL LPFIDSFQRV DLRTRAFNVP PCKLASKDGA VLSVGADVQF RIWDPVLSVM TVKDLNTATR MTAQNAMTKA LLKRPLREIQ MEKLKISDQL LLEINDVTRA WGLEVDRVEL AVEAVLQPPQ DSPAGPNLDS TLQQLALHFL GGSMNSMAGG APSPGPADTV EMVSEVEPPA PQVGARSSPK QPLAEGLLTA LQPFLSEALV SQVGACYQFN VVLPSGTQSA YFLDLTTGRG RVGHGVPDGI PDVVVEMAEA DLRALLCREL RPLGAYMSGR LKVKGDLAMA MKLEAVLRAL K (79-398 aa encoded by BC034379)
靶标信息
Stomatin-like protein 1 (STOML1) is encoded by the STOML1 gene located on chromosome 17 in humans. It is part of a family of five mammalian genes that encode peripheral membrane proteins involved in modulating ion channel functions. STOML1 is known to interact specifically with members of the acid-sensing ion channel (ASIC) family, influencing their proton sensitivity. These interactions help regulate ion transport and signaling pathways, which are critical for cellular homeostasis. In addition, STOML1 has been studied in the context of oral squamous cell carcinoma (OSCC), where it is often overexpressed along with STOML2, potentially affecting cancer progression. Structurally, STOML1 contains a stomatin domain which is crucial for its role in membrane association and ion channel modulation. Its expression in olfactory sensory neurons (OSNs) is comparatively lower than other family members, but it still contributes to the localization and functional integrity of related proteins in these cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EPB72-like 1; EPB72-like protein 1; Protein unc-24 homolog; SLP-1; stomatin (EBP72)-like 1; stomatin (EPB72)-like 1; stomatin-like 1; Stomatin-like protein 1; Stomatin-related protein; STORP
基因别名: 1810015E19Rik; AI847431; hUNC-24; MSTP019; RGD1559463; SLP-1; SLP1; STOML1; STORP; UNC24; WPB72
UniProt ID: (Human) Q9UBI4, (Mouse) Q8CI66
Entrez Gene ID: (Human) 9399, (Rat) 300748, (Mouse) 69106
