Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Syntaxin 18 mainly localizes to the endoplasmic reticulum (ER), and functions in transport between the ER and Golgi. Syntaxin 18 also plays a role in ER-mediated phagocytosis, possibly by regulating the specific fusion of the ER and plasma or phagosomal membranes.
蛋白别名: Cell growth-inhibiting gene 9 protein; Syntaxin-18
基因别名: GIG9; STX18; Ufe1
UniProt ID: (Human) Q9P2W9
Entrez Gene ID: (Human) 53407
分子生物学功能: SNARE protein