应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:500-1:2,000 | - |
免疫细胞化学 (ICC/IF) |
1:50-1:200 | - |
产品规格 | |
---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human SUMO3 |
偶联物 |
Unconjugated |
形式 |
liquid |
浓度 |
1.43 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.3, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2806162 |
Immunogen sequence: MSEEKPKEGV KTENDHINLK VAGQDGSVVQ FKIKRHTPLS KLMKAYCERQ GLSMRQIRFR FDGQPINETD TPAQLEMEDE DTIDVFQQQT GG; Positive Samples: U-87MG, LO2, Mouse liver, Mouse kidney, Mouse small intestine, Mouse heart, Rat liver, Rat heart; Cellular Location: Cytoplasm, Nucleus, PML body
Small ubiquitin-related modifier proteins are members of the ubiquitin-like protein family. SUMO-3 regulates Amyloid beta generation and may be critical in the onset or progression of Alzheimer's disease. SUMO-2/3 forms poly-. SUMO-1, 2, and 3 proteins localize to the nuclear membrane, nuclear bodies, and cytoplasm, respectively. SUMOylation is essential for mammalian cell cycle regulation, SUMO-2/3 localizes to centromeres and condensed chromosomes where binds CENP-E.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Small ubiquitin-related modifier 3; SMT3 (supressor of mif two, 3) homolog 1; SMT3 homolog 1; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 3; Smt3A; SUMO-2; SUMO-3; Ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B
基因别名: 2810014B19Rik; D10Ertd345e; SMT3A; Smt3B; SMT3H1; SUMO-3; SUMO3
UniProt ID: (Human) P55854, (Rat) Q5XIF4, (Mouse) Q9Z172
Entrez Gene ID: (Human) 6612, (Rat) 499417, (Mouse) 20610