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Positive Samples: MCF7; Cellular Location: Cytoplasm, Nucleus, PML body
Small ubiquitin-related modifier proteins are members of the ubiquitin-like protein family. SUMO-3 regulates Amyloid beta generation and may be critical in the onset or progression of Alzheimer's disease. SUMO-2/3 forms poly-. SUMO-1, 2, and 3 proteins localize to the nuclear membrane, nuclear bodies, and cytoplasm, respectively. SUMOylation is essential for mammalian cell cycle regulation, SUMO-2/3 localizes to centromeres and condensed chromosomes where binds CENP-E.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Small ubiquitin-related modifier 3; SMT3 (supressor of mif two, 3) homolog 1; SMT3 homolog 1; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 3; Smt3A; SUMO-2; SUMO-3; Ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B
基因别名: 2810014B19Rik; D10Ertd345e; SMT3A; Smt3B; SMT3H1; SUMO-3; SUMO3
UniProt ID: (Human) P55854, (Rat) Q5XIF4, (Mouse) Q9Z172
Entrez Gene ID: (Human) 6612, (Rat) 499417, (Mouse) 20610
