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Proteintech
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Immunogen sequence: MSGKTKARR AAMFFRRCSE DASGSASGNA LLSEDENPDA NGVTRSWKII LSTMLTLTFL LVGLLNHQWL KETDVPQKSR QLYAIIAEYG SRLYKYQARL RMPKEQLELL KKESQNLENN FRQILFLVEQ IDVLKALLRD MKDGMDNNHN WNTHGDPVED PDHTEEVSNL VNYVLKKLRE DQVEMADYAL KSAGASIIEA GTSESYKNNK AKLYWHGIGF LNHEMPPDI (1-228 aa encoded by BC026189 )
As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hypothetical protein MGC33329; Sad1 and UNC84 domain containing 1; Sad1/unc-84 domain-containing protein 1; SUN domain-containing protein 3
基因别名: SUN3; SUNC1
UniProt ID: (Human) Q8TAQ9, (Mouse) Q5SS91
Entrez Gene ID: (Human) 256979, (Mouse) 194974