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Proteintech
SUPV3L1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
12826-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SUPV3L1 Fusion Protein Ag3542 (441-786 aa encoded by BC036112)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.13 mg/mL
规格
19.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: YSLIKPSIN EKGERELEPI TTSQALQIAG RAGRFSSRFK EGEVTTMNHE DLSLLKEILK RPVDPIRAAG LHPTAEQIEM FAYHLPDATL SNLIDIFVDF SQVDGQYFVC NMDDFKFSAE LIQHIPLSLR VRYVFCTAPI NKKQPFVCSS LLQFARQYSR NEPLTFAWLR RYIKWPLLPP KNIKDLMDLE AVHDVLDLYL WLSYRFMDMF PDASLIRDLQ KELDGIIQDG VHNITKLIKM SETHKLLNLE GFPSGSQSRL SGTLKSQARR TRGTKALGSK ATEPPSPDAG ELSLASRLVQ QGLLTPDMLK QLEKEWMTQQ TEHNKEKTES GTHPKGTRRK KKEPDSD (441-786 aa encoded by BC036112 )
靶标信息
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules (PubMed:29967381). ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: hsuv3p; suppressor of var1 3-like protein 1; suppressor of var1, 3-like 1; suppressor of var1, 3-like 1(SUV3); SUV3-like helicase; SUV3-like protein 1; unnamed protein product
基因别名: 6330443E10Rik; SUV3
UniProt ID: (Human) Q8IYB8, (Mouse) Q80YD1, (Rat) Q5EBA1
Entrez Gene ID: (Human) 6832, (Mouse) 338359, (Rat) 294385
mitochondrial RNA catabolic process
mitochondrial mRNA catabolic process
positive regulation of mitochondrial RNA catabolic process
mitochondrial RNA 3'-end processing
DNA recombination
RNA catabolic process
mitochondrion organization
positive regulation of cell growth
mitochondrial ncRNA surveillance
mitochondrial mRNA surveillance
negative regulation of apoptotic process
mitochondrial RNA surveillance
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