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SV2A Polyclonal Antibody
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SV2A Antibody (BS-2407R) in Flow
Molt-4 (Positive) and A549 (Negative control) cells (black) were fixed with 4% PFA for 10min at room temperature, permeabilized with 20% PBST for 20 min at room temperature, and incubated in 5% BSA blocking buffer for 30 min at room temperature. Cells were then stained with SV2A Antibody (bs-2407R) at 1:50 dilution in blocking buffer and incubated for 30 min at room temperature, washed twice with 2% BSA in PBS, followed by secondary antibody(blue) incubation for 40 min at room temperature. Acquisitions of 20,000 events were performed. Cell... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
BS-2407R
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human SV2A, amino acids 451-550.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This protein plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.It is identified as the brain binding-site for the antiepileptic drug levetiracetam/lev.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium regulator SV2A; solute carrier family 22 member B1; synaptic vesicle glycoprotein 2 a; synaptic vesicle protein 2; synaptic vesicle protein 2A; synaptic vesicle transmembrane transporter (SV2) RNA; unnamed protein product
基因别名: DEE113; mKIAA0736; SLC22B1; SV2
UniProt ID: (Human) Q7L0J3, (Mouse) Q9JIS5, (Rat) Q02563
Entrez Gene ID: (Human) 9900, (Mouse) 64051, (Rat) 117559
cellular calcium ion homeostasis
chemical synaptic transmission
regulation of gamma-aminobutyric acid secretion
synaptic vesicle priming
protein localization to synapse
transmembrane transport
negative regulation of excitatory postsynaptic potential
modulation of inhibitory postsynaptic potential
neurotransmitter transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
