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PA1-4977 detects Swi6 from S. pombe samples.
PA1-4977 has been successfully used in Western blot and immunoprecimmunoprecipitationitation applications. Western blot analysis of crude extract of S. pombe detects a protein with an apparent molecular size of 53 kD.
Swi6 protein of fission yeast is a functional and structural homolog of HP1 (Heterochromatin Protein 1) of animals and is involved in the formation of heterochromatin structure by binding to centromere, telomere and silent mating-type locus. It is also involved in silencing the genes and sister chromatid cohesion by binding to histone H3 methylated at Lys9 and the cohesin subunit Psc3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cell-cycle box factor subunit SWI6; MBF subunit P90; Regulatory protein SWI6; Trans-acting activator of HO endonuclease gene
基因别名: L9470.8; PSL8; SDS11; SWI6; YLR182W
Entrez Gene ID: (Baker's yeast) 850879
分子生物学功能: hydrolase