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Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Desmuslin; Synemin; synm
基因别名: 4930412K21Rik; AI852401; Dmn; E130104F11; Kiaa0353; Syn; Synemin; Synm
UniProt ID: (Mouse) Q70IV5
Entrez Gene ID: (Rat) 308709, (Mouse) 233335