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Proteintech
SYNPO2L Polyclonal Antibody
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产品信息
21480-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SYNPO2L Fusion Protein Ag15683 (35-389 aa encoded by BC142635)
偶联物
形式
Liquid
浓度
0.26 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LQRAESLQE KSIKEAKTKC RTIASLLTAA PNPHSKGVLM FKKRRQRAKK YTLVSFGAAA GTGAEEEDGV PPTSESELDE EAFSDARSLT NQSDWDSPYL DMELARAGSR ASEGQGSGLG GQLSEVSGRG VQLFEQQRQR ADSSTQELAR VEPAAMLNGE GLQSPPRAQS APPEAAVLPP SPLPAPVASP RPFQPGGGAP TPAPSIFNRS ARPFTPGLQG QRPTTTSVIF RPLAPKRAND SLGGLSPAPP PFLSSQGPTP LPSFTSGVPS HAPVSGSPST PRSSGPVTAT SSLYIPAPSR PVTPGGAPEP PAPPSAAAMT STASIFLSAP LRPSARPEAP APGPGAPEPP SAREQR (35-389 aa encoded by BC142635)
靶标信息
SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Synaptopodin 2-like protein
基因别名: 1110054M18Rik; Chap; RGD1565434; SYNPO2L
UniProt ID: (Human) Q9H987, (Mouse) Q8BWB1
Entrez Gene ID: (Human) 79933, (Mouse) 68760, (Rat) 305675
