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Abnova
SYT4 Monoclonal Antibody (5F8)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00006860-M04
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG3, kappa
分类
Monoclonal
类型
Antibody
克隆号
5F8
抗原
SYT4 (NP_065834, 1 a.a. approximately 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.36 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MAPITTSREE FDEIPTVVGI FSAFGLVFTV SLFAWICCQR KSSKSNKTPP YKFVHVLKGV DIYPENLNSK KKFGADDKNE VKNKPAVPKN SLHLDLEKR
靶标信息
May be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. Plays a role in dendrite formation by melanocytes (PubMed:23999003).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: synaptotagmin IV; Synaptotagmin4; sytIV; unnamed protein product
基因别名: HsT1192
UniProt ID: (Human) Q9H2B2
Entrez Gene ID: (Human) 6860
vesicle fusion
memory
positive regulation of glutamate secretion
regulation of dopamine secretion
vesicle-mediated transport
regulation of calcium ion-dependent exocytosis
regulation of endocytosis
regulation of vesicle fusion
negative regulation of catecholamine secretion
negative regulation of calcium ion-dependent exocytosis
positive regulation of calcium ion-dependent exocytosis
negative regulation of short-term neuronal synaptic plasticity
negative regulation of protein secretion
calcium-dependent activation of synaptic vesicle fusion
dense core granule cytoskeletal transport
regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission
regulation of postsynaptic dense core vesicle exocytosis
negative regulation of secretion by cell
positive regulation of dendrite extension
positive regulation of dense core granule exocytosis
negative regulation of retrograde trans-synaptic signaling by neuropeptide
negative regulation of synaptic vesicle exocytosis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
