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Invitrogen
SYTL5 Polyclonal Antibody
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产品信息
PA5-55284
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KQVNVLGTDV VRQSILRRSP AEEVQSQEQT RQDAEKSDTS PVAGKKASHD GPKRKGFLLS KFRSATRGEI ITPKTDTGRS YSLDLDGQHF RSLKSPPGSD RGSTGSSDLN DQEP
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 75%.
靶标信息
SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: exophilin 9; synaptotagmin-like 5; Synaptotagmin-like protein 5
基因别名: SLP5; SYTL5
UniProt ID: (Human) Q8TDW5
Entrez Gene ID: (Human) 94122
