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Invitrogen
Seniprutug Humanized Recombinant Human Monoclonal Antibody
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产品信息
MA562573
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
形式
Liquid
浓度
1.34 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Seniprutug is a biosimilar that functions as an antagonist to TRBV9, a protein associated with T cell receptor beta variable 9, playing a crucial role in adaptive immune responses and receptor-mediated signaling pathways. TRBV9 is localized at the cell membrane and consists of 114 amino acid residues with a molecular weight of approximately 12.6 kilodaltons. The biosimilar Seniprutug, first developed by Biocad CJSC, is currently undergoing phase 3 trials and targets immune system diseases such as non-radiographic axial spondyloarthritis. Seniprutug is utilized as both a therapeutic agent and as research grade material, aiding in the immunodetection of TRBV9 for various studies in immunology, particularly in conditions affecting the skin, musculoskeletal, and infectious disease domains.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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