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Positive control: Shaker over-expressed HEK293
Cellular location: Membrane.
The assemblage of specific ion channels and receptors at synaptic sites is crucial for signaling between pre- and post-synaptic cells. DLG (Drosophila discs-large gene) is co-localized with Shaker K1 channels, which are clustered at glutamatergic synapses. DLG-Shaker interactions are required in vivo for shaker clustering at the neuromuscular junction. The channel protein Shaker which is properly synthesized, glycosylated, folded, assembled and delivered to the plasma membrane is very important for the potassium channel function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CG12348-PA; CG12348-PB; CG12348-PC; CG12348-PD; CG12348-PE; CG12348-PF; CG12348-PH; CG12348-PI; CG12348-PJ; CG12348-PK; CG12348-PL; CG12348-PM; CG12348-PQ; CG12348-PS; CG12348-PT; F-c transcription unit; minisleep; Potassium voltage-gated channel protein Shaker; Protein minisleep; Sh-PA; Sh-PB; Sh-PC; Sh-PD; Sh-PE; Sh-PF; Sh-PH; Sh-PI; Sh-PJ; Sh-PK; Sh-PL; Sh-PM; Sh-PQ; Sh-PS; Sh-PT; Shaker-downheld; unnamed protein product
基因别名: BcDNA:GH03046; CG12348; CG17860; CG7640; Dmel\CG12348; Dmel_CG12348; EKO; F-c; K[[v]]1; Kv1; minisleep; mns; SH; Sha; Shw; V-I
UniProt ID: (Fruit fly) P08510
Entrez Gene ID: (Fruit fly) 32780
分子生物学功能: voltage-gated ion channel