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Invitrogen
Simvastatin Recombinant Mouse Monoclonal Antibody (3E9)
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Simvastatin Antibody (MA566320) in SDS-PAGE
SDS-PAGE characterization of Simvastatin under reducing conditions. Lane M: Protein marker (kDa); Lane SVT: Purified Simvastatin Recombinant Monoclonal (Product # MA566320). Simvastatin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-673.
产品信息
MA566320
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3E9
抗原
Conjugate of QND hapten and KLH.
偶联物
形式
Liquid
浓度
5.6 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Simvastatin is a biosimilar HMG-CoA reductase inhibitor primarily used to lower lipid levels and reduce the risk of cardiovascular events such as myocardial infarction and stroke. Structurally, simvastatin contains a lactone ring and is administered as an inactive prodrug, which is converted in the body to its active beta-hydroxy acid form. The gene location for simvastatin biosimilars is not directly applicable as it is a synthetic compound rather than a biological product derived from genetic material. Functionally, simvastatin works by inhibiting the HMG-CoA reductase enzyme, which plays a crucial role in cholesterol synthesis in the liver. Studies have evaluated the bioequivalence of simvastatin biosimilars, comparing pharmacokinetics and therapeutic efficacy to reference formulations, ensuring similar safety and effectiveness profiles.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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