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Sinomenine is an isoquinoline alkaloid primarily extracted from the roots and stems of Sinomenium acutum, a traditional Chinese medicinal plant. It has been utilized as an anti-inflammatory agent in China for over three decades, particularly in the treatment of rheumatoid arthritis (RA). Sinomenine's pharmacological actions are diverse, including immunosuppressive, antitumor, neuroprotective, and antiarrhythmic effects. The compound functions by modulating inflammatory pathways, although its precise molecular mechanisms in RA are not fully elucidated. Sinomenine derivatives have been developed to enhance its therapeutic efficacy, demonstrating improved anti-inflammatory effects in various animal models. The ongoing research continues to explore its potential as a multi-therapeutic agent, expanding its application beyond RA treatment.
仅用于科研。不用于诊断过程。未经明确授权不得转售。