Antibodies Inc

Slo1/BKAlpha Potassium Channel Monoclonal Antibody (L6/23), FL490

Name: Slo1\/BKAlpha Potassium Channel Monoclonal Antibody (L6\/23), FL490
Brand: Antibodies Inc
SKU: 75-408-FL490

查看其他27个KCNMA1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

Immunogen image

Immunogen Image Slo1/BKAlpha Potassium Channel Monoclonal Antibody (L6/23), FL490

产品信息

75-408-FL490

应用

建议稀释比

已发表文章

免疫组化（冰冻） (IHC (F))

Assay-dependent

免疫细胞化学 (ICC/IF)

Assay-dependent

酶联免疫吸附实验 (ELISA)

Assay-dependent

产品规格

种属反应

Mouse, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

L6/23

抗原

Fusion protein amino acids 690-1196 (cytoplasmic C-terminus) of mouse Slo1 (accession number Q08460) produced recombinantly in E. Coli.

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偶联物

FL490 FL490 FL490

激发/发射光谱

491/515 nm

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Dry ice (international)

产品详细信息

For maximum recovery of product, centrifuge the vial prior to removing the cap.

靶标信息

Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: BK channel; BK channel alpha subunit; BKCA alpha; calcium-activated potassium channel alpha subunit; Calcium-activated potassium channel subunit alpha-1; Calcium-activated potassium channel, subfamily M subunit alpha-1; K(VCA)alpha; KCa1.1; Maxi K channel; MaxiK; mSlo1; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; Slo homolog; Slo-alpha; Slo1; Slowpoke homolog

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基因别名: 5730414M22Rik; BKCa; Kcnma; Kcnma1; KCNMA1b; KCNMA1c; MaxiK; mSlo; mSlo1; Slo; Slo1

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UniProt ID: (Mouse) Q08460, (Rat) Q62976

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Entrez Gene ID: (Mouse) 16531, (Rat) 83731

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功能