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Invitrogen
Smallpox Virus B5R Monoclonal Antibody (1J2F3)
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Smallpox Virus B5R Antibody (MA1-41212) in WB
Western blot analysis of Smallpox Virus B5R in recombinant fusion protein. Samples were incubated with Smallpox Virus B5R monoclonal antibody (Product # MA1-41212) using a dilution of 0.2 µg/mL. (A) recombinant fusion protein containing amino acids 33-47 and (B) fusion partner without these amino acids.
产品信息
MA1-41212
产品规格
种属反应
Virus
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1J2F3
抗原
Amino acids 33-47 of the B5R protein.
偶联物
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with Bovinepox virus, Ectromelia virus, Monkeypox virus, Rabbitpox virus, and vaccinia virus.
Immunogen sequence: IQEYNLIRTY KKVDK
靶标信息
B5R is an EEV-specific Type I membrane glycoprotein essential for EEV formation. Vaccinia virus, a member of Poxviridae family, is a dsDNA enveloped virus. It consists of 4 types of virion stages among which extracellular enveloped virus (EEV) is critical for cell-to-cell and long range viral infection. Some cellular antigens are associated with EEV and these vary with the cell type used to grow the virus. B5R consists of a large ectodomain containing regions similar to SCR domains of complement regulatory proteins followed by a transmembrane region and a cytoplasmic tail. B5R is essential for efficient wrapping of IMV, actin tail formation, normal plaque size, virus virulence, and for EEV formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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