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Invitrogen
IL-17AF/Albumin (Sonelokimab Biosimilar) Recombinant Humanized mouse Monoclonal Antibody
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产品信息
MA5-42290
产品规格
种属反应
Human
宿主/亚型
Artificial Control
/ VH-VH
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human ALB,IL17A
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.42 mg/mL
规格
100 µg
纯化类型
Metal-chelate chromatography
保存液
30mM histidine, pH 5.8, with 10% sucrose, 0.02% Tween 80
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
Isotype of this product is: VH-VH'-VH
靶标信息
IL-17A and IL-17F are well-characterized homodimeric cytokines secreted by T helper 17 (Th17) cells, gamma-delta T cells and several subsets of innate lymphoid cells. Somewhat less appreciated, IL-17A and IL-17F subunits can also form the heterodimer, IL-17AF. Together, these three dimers signal through the IL-17RA/IL-17RC receptor complex to mediate immune responses at mucosal interfaces and are found at lesion sites in inflammatory bowel disease, asthma, atopic dermatitis and rheumatoid arthritis.
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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