Proteintech

Sortilin Polyclonal Antibody

Name: Sortilin Polyclonal Antibody
Brand: Proteintech
SKU: 12369-1-AP

10 篇参考文献

查看其他19个Sortilin抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (10)

Sortilin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 10

Sortilin Antibody (12369-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human brain tissue slide using 12369-1-AP ( Sortilin antibody at dilution of 1:100 (under 40x lens).

Sortilin Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

Sortilin Antibody in Flow Cytometry (Flow)

Sortilin Antibody in Immunoprecipitation (IP)

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Immunogen image

Immunogen Image Sortilin Polyclonal Antibody

产品信息

12369-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:5,000

查看6篇已发表文章 6篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:500

免疫组织化学（多聚甲醛固定） (IHC (PFA))

1:400

免疫细胞化学 (ICC/IF)

查看4篇已发表文章 4篇已发表文章

流式细胞分析 (Flow)

0.2 µg/1x10^6 cells

免疫沉淀 (IP)

0.5-4.0 µg

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Sortilin Fusion Protein Ag2997 (481-831 aa encoded by BC023542)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.23 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: EPNAVGIVI AHGSVGDAIS VMVPDVYISD DGGYSWTKML EGPHYYTILD SGGIIVAIEH SSRPINVIKF STDEGQCWQT YTFTRDPIYF TGLASEPGAR SMNISIWGFT ESFLTSQWVS YTIDFKDILE RNCEEKDYTI WLAHSTDPED YEDGCILGYK EQFLRLRKSS VCQNGRDYVV TKQPSICLCS LEDFLCDFGY YRPENDSKCV EQPELKGHDL EFCLYGREEH LTTNGYRKIP GDKCQGGVNP VREVKDLKKK CTSNFLSPEK QNSKSNSVPI ILAIVGLMLV TVVAGVLIVK KYVCGGRFLV HRYSVLQQHA EANGVDGVDA LDTASHTNKS GYHDDSDEDL LE (481-831 aa encoded by BC023542)

靶标信息

Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Sortilin is required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). It is also required for protein transport from the Golgi apparatus to the endosomes. Sortilin promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also, Sortilin acts as a receptor for neurotensin.

仅用于科研。不用于诊断过程。未经明确授权不得转售。