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Invitrogen
Sortilin Polyclonal Antibody
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产品信息
OSS00010W
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from rat Sortilin conjugated to blue carrier protein was used as the antigen.
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 100 µL of distilled water.
The peptide shares 95% identity with mouse's.
靶标信息
Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Sortilin is required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). It is also required for protein transport from the Golgi apparatus to the endosomes. Sortilin promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also, Sortilin acts as a receptor for neurotensin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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