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Invitrogen
Stabilin 2 Polyclonal Antibody
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Stabilin 2 Antibody (PA5-87617) in WB
Western blot analysis of Stabilin 2 in extracts of various cell lines. Samples were incubated with Stabilin 2 Polyclonal antibody (Product # PA5-87617) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.
产品信息
PA5-87617
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1550-1850 of human STAB2 (NP_0600349)
偶联物
形式
Liquid
浓度
2.52 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GKVCTLINVC LTKNGGCSEF AICNHTGQVE RTCTCKPNYI GDGFTCRGSI YQELPKNPKT SQYFFQLQEH FVKDLVGPGP FTVFAPLSAA FDEEARVKDW DKYGLMPQVL RYHVVACHQL LLENLKLISN ATSLQGEPIV ISVSQSTVYI NNKAKIISSD IISTNGIVHI IDKLLSPKNL LITPKDNSGR ILQNLTTLAT NNGYIKFSNL IQDSGLLSVI TDPIHTPVTL FWPTDQALHA LPAEQQDFLF NQDNKDKLKE YLKFHVIRDA KVLAVDLPTS TAWKTLQGSE LSVKCGAGRD I; Positive Samples: HepG2, BT-474, Mouse liver, Mouse eye, Mouse kidney, Rat liver; Cellular Location: Cell membrane, Cytoplasm, Single-pass type I membrane protein
靶标信息
This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD44-like precursor FELL; DKFZP434E0321; FAS1 EGF-like and X-link domain containing adhesion molecule-2; FAS1 EGF-like and X-link domain-containing adhesion molecule 2; fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-2; Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2; FEEL-2; FELL-2; HAREFELL2; hepatic hyaluronan clearance receptor; Hyaluronan receptor for endocytosis; hyaluronic acid receptor for endocytosis; scavenger receptor FEEL-2; STAB2; stab2 {ECO:0000250|UniProtKB:Q8WWQ8}; Stabilin-2; Stabilin2
基因别名: FEEL-2; FEEL2; FELE-2; FELL; FELL2; FEX2; HARE; MFEEL-2; SCARH1; STAB-2; STAB2
UniProt ID: (Human) Q6ZMK2, (Mouse) Q8R4U0
Entrez Gene ID: (Human) 55576, (Mouse) 192188, (Rat) 282580
