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Invitrogen
Staphylococcus aureus neutral proteinase Polyclonal Antibody
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Staphylococcus aureus neutral proteinase Antibody (PA5-144507) in WB
Western blot analysis of Staphylococcus aureus neutral proteinase in recombinant protein using a dilution of 1:2,000. Samples were incubated with Staphylococcus aureus neutral proteinase polyclonal antibody (Product # PA5-144507). Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 39.3 kDa. Observed band size: 50 kDa.
产品信息
PA5-144507
产品规格
种属反应
Bacteria
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Staphylococcus aureus Zinc metalloproteinase aureolysin (aur) (210-509AA)
偶联物
形式
Liquid
浓度
4.18 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% Proclin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Plays an essential role in immune evasion by helping bacteria to resist complement-mediated killing by neutrophils. Inhibits the deposition of host C3b on bacterial surfaces and the release of the chemoattractant C5a by cleaving the central complement protein C3. The cleavage site renders the C3b molecule vulnerable to proteolytic degradation by host regulators (PubMed:21502375). Cleaves and inactivates host SERPINA1, which is an endogenous protease inhibitor essential for controlling neutrophil serine protease elastase (PubMed:3533918). Also plays an essential role in the cleavage and subsequent activation of the serine protease SspA (glutamyl endopeptidase) which is involved in colonization and infection of human tissues (PubMed:17878159).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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