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Rockland
TACI Polyclonal Antibody
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TACI Antibody (600-401-EZ4) in ICC/IF
Immunocytochemistry of TACI antibody. Cells: K562 cells. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: TACI antibody at 2 µg/mL for 1 hr at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: TACI is localized in the cell membrane. Staining: TACI as precipitated brown signal with hematoxylin blue nuclear counterstain.
产品信息
600-401-EZ4
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-TACI antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide mapping at the N-terminus of human TACI.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD267; Transmembrane activator and CAML interactor; tumor necrosis factor receptor 13B; Tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor superfamily, member 13B
基因别名: CD267; CVID; CVID2; IGAD2; RYZN; TACI; TNFRSF13B; TNFRSF14B
UniProt ID: (Human) O14836
Entrez Gene ID: (Human) 23495
