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产品信息
PA5-50560
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:2,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:25-1:100 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide corresponding to residues near the N terminal of human tachykinin receptor 2 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.8 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2636013 |
产品详细信息
The antibody detects endogenous levels of total Nk2 / TACR2 protein.
靶标信息
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: neurokinin 2 receptor; Neurokinin A receptor; NK-2 receptor; NK-2R; NK2; seven transmembrane helix receptor; SK receptor; SKR; substance K receptor; Substance-K receptor; Tachykinin receptor 2
基因别名: NK2R; NKNAR; SKR; TAC2R; TACR2
UniProt ID: (Human) P21452
Entrez Gene ID: (Human) 6865
分子生物学功能:
G-protein coupled receptor
muscle contraction
cell surface receptor signaling pathway
tachykinin receptor signaling pathway
chemical synaptic transmission
excretion
positive regulation of acetylcholine secretion, neurotransmission
intestine smooth muscle contraction
negative regulation of luteinizing hormone secretion
operant conditioning
positive regulation of vascular permeability
positive regulation of smooth muscle contraction
response to electrical stimulus
prolactin secretion
positive regulation of uterine smooth muscle contraction
