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Invitrogen
TAF4B Polyclonal Antibody
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产品信息
PA5-56014
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PHLVPFLKKS VVALRQLLPN SQSFIQQCVQ QTSSDMVIAT CTTTVTTSPV VTTTVSSSQS EKSIIVSGAT APRTVSVQTL NPLAGPVGAK AGVVTLHSVG PTAATGGTTA GTGLLQTSKP LVTSVANTVT TVSLQPEKPV VSGTAVT
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 70%.
靶标信息
TAF II p105, also called TAF4B, is a celltype specific transcriptional co-activator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell-specific octamerdependent transcription. Additionally, TAF II p105 plays an important role in co-activating the transcription factor NFkB and is essential for activation of anti-apoptotic genes such as TNFAIP3. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine-rich domains, such as the transcription factor CREB.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: TAF(II)105; TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa; TAFII-105; TATA box binding protein (TBP)-associated factor 4B; TATA box binding protein (TBP)-associated factor, RNA polymerase II, C2, 105kD; TATA box binding protein associated factor 4b; Transcription initiation factor TFIID 105 kDa subunit; Transcription initiation factor TFIID subunit 4B
基因别名: SPGF13; TAF2C2; TAF4B; TAFII105
UniProt ID: (Human) Q92750
Entrez Gene ID: (Human) 6875
