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Invitrogen
TAF5 Polyclonal Antibody
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产品信息
PA5-96612
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 656-800 of human TAF5 (NP_0088822)
偶联物
形式
Liquid
浓度
2.33 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VLNGNCVRIF TGHKGPIHSL TFSPNGRFLA TGATDGRVLL WDIGHGLMVG ELKGHTDTVC SLRFSRDGEI LASGSMDNTV RLWDAIKAFE DLETDDFTTA TGHINLPENS QELLLGTYMT KSTPVVHLHF TRRNLVLAAG AYSPQ; Positive Samples: Mouse brain; Cellular Location: Nucleus
靶标信息
TFIID is a general transcription factor which initiates preinitiation complex assembly through direct interaction with the TATA promoter element. It is a multisubunit complex consisting of a small TATA-binding polypeptide andother TATA-binding protein (TBP)-associated factors (TAFs). Although native TFIID can mediate both activator-independent (basal) and activator-dependent transcription in reconstituted systems, TBP can mediate only basal transcription. TAF II p100 (TBP-associated factor II100), also known as TAF5 or TAFII100, is the third largest subunit of human TFIID. It contains six WD40 repeats at the C-terminus and has an N-terminus capable of forming a flexible dimer. TAF II p100 plays an important role in forming the scaffold that is crucial for the assembly of the TFIID complex. TAF II p100 may also be involved in the stabilization of TAF interactions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: TAF(II)100; TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa; TAFII-100; TAFII100; TATA box binding protein (TBP)-associated factor 2D; TATA box binding protein (TBP)-associated factor, RNA polymerase II, D, 100kD; TATA box binding protein associated factor 5; Tbp-associated factor 5; transcription initiation factor TFIID 100 kD subunit; Transcription initiation factor TFIID 100 kDa subunit; Transcription initiation factor TFIID subunit 5
基因别名: 6330528C20Rik; AV117817; TAF(II)100; TAF2D; TAF5; TAFII-100; TAFII100
UniProt ID: (Human) Q15542, (Mouse) Q8C092
Entrez Gene ID: (Human) 6877, (Mouse) 226182, (Rat) 294018
DNA-templated transcription, initiation
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
viral process
chromatin modification
histone acetylation
snRNA transcription from RNA polymerase II promoter
regulation of signal transduction by p53 class mediator
transcription, DNA-templated
biological_process
