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Invitrogen
TAFA3 Polyclonal Antibody
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产品信息
PA5-63210
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: AALQPPTATV LVQQGTCEVI A
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 86%.
靶标信息
The TAFA3 gene encodes a protein that is part of the TAFA family of chemokine-like proteins, involved in modulating immune responses and inflammatory processes. TAFA3 is particularly implicated in the regulation of neuroinflammatory and neuroprotective activities in the central nervous system. It functions as a signaling molecule that can influence cell survival, proliferation, and migration, contributing to homeostasis in neural tissue and promoting recovery following injury. TAFA3 has been studied for its role in neuroprotection, where it helps shield neurons from damage caused by oxidative stress and inflammatory stimuli, making it significant in neurodegenerative conditions. Apart from its neuroprotective capabilities, TAFA3 may also be involved in the systemic modulation of inflammation, affecting immune cell trafficking and responses. Research into TAFA3 continues to unveil its multifaceted role in health and disease, highlighting potential therapeutic avenues for targeting this protein in conditions characterized by excessive inflammation or neurodegeneration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chemokine-like protein TAFA-3; family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
基因别名: FAM19A3; TAFA-3; TAFA3
UniProt ID: (Human) Q7Z5A8
Entrez Gene ID: (Human) 284467
