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Invitrogen
TAS2R41 Polyclonal Antibody
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产品信息
PA5-144106
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Taste receptor type 2 member 41 protein (205-234AA)
偶联物
形式
Liquid
浓度
3 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% Proclin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
TAS2R41 is a receptor that may play a role in the perception of bitterness and belongs to the G-protein receptor superfamily. TAS2R41 is expressed mainly in taste receptor cells of the tongue and the palate eptithelia. Structurally, the TAS2R41 gene encodes a seven trans-membrane receptor protein and is clustered together with eight other taste receptor genes on chromosome 7. The compound chloramphenicol is an agonist for the TAS2R41 protein. Further, TAS2R41 may play a role in sensing the chemical composition of the gastrointestinal content. The activity of TAS2R41 may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. TAS2R41 is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC119928; MGC119929; T2R41; T2R59; Taste receptor type 2 member 41; Taste receptor type 2 member 59; taste receptor, type 2, member 41
基因别名: T2R41; T2R59; TAS2R41
UniProt ID: (Human) P59536
Entrez Gene ID: (Human) 259287
