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Invitrogen
TAUT Polyclonal Antibody
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产品信息
PA5-53269
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human TAUT
偶联物
形式
Liquid
浓度
Lot-Specific
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: ATYYLFQSFQ KELPWAHCNH SWNTPHCMED TMRKNKSVWI TISSTNFTSP VIEFWERNVL SLSPGIDHP
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 83%.
靶标信息
Taurine is an abundant organic osmolyte that possesses antioxidant and immunomodulatory properties and plays a role in cell volume homeostasis. Taurine is taken up into cells via the taurine transporter (TAUT). TAUT, which is sodium- and chloride-dependent, is a multi-pass membrane protein belonging to the sodium neurotransmitter symporter (SNF) family of proteins. TNF alpha upregulates TAUT expression, while phosphorylation on Serine 322 downregulates it. Overexpression of TAUT protects renal cells from cisplatin-induced nephrotoxicity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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