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Proteintech
TAX1BP1 Polyclonal Antibody
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产品信息
14424-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TAX1BP1 Fusion Protein Ag5789 (454-789 aa encoded by BC050358)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: KECQRLQKQ INKLSDQSAN NNNVFTKKTG NQQKVNDASV NTDPATSAST VDVKPSPSAA EADFDIVTKG QVCEMTKEIA DKTEKYNKCK QLLQDEKAKC NKYADELAKM ELKWKEQVKI AENVKLELAE VQDNYKELKR SLENPAERKM EGQNSQSPQC FKTCSEQNGY VLTLSNAQPV LQYGNPYASQ ETRDGADGAF YPDEIQRPPV RVPSWGLEDN VVCSQPARNF SRPDGLEDSE DSKEDENVPT APDPPSQHLR GHGTGFCFDS SFDVHKKCPL CELMFPPNYD QSKFEEHVES HWKVCPMCSE QFPPDYDQQV FERHVQTHFD QNVLNFD (454-789 aa encoded by BC050358 )
靶标信息
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Tax1 (human T-cell leukemia virus type I) binding protein 1; Tax1-binding protein 1; Tax1-binding protein 1 homolog; TRAF6-binding protein; TRAF6-binding protein homolog
基因别名: 1200003J11Rik; 1700069J21Rik; AA930106; CALCOCO3; D6Ertd404e; D6Ertd772e; PRO0105; T6BP; TAX1BP1; TXBP151
UniProt ID: (Human) Q86VP1, (Mouse) Q3UKC1
Entrez Gene ID: (Human) 8887, (Mouse) 52440
