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产品信息
PA5-50279
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:100-1:300 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Fusion protein corresponding to a region derived from internal residues of human Tax1 (human T-cell leukemia virus type I) binding protein 1 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
2 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635732 |
产品详细信息
The antibody detects endogenous levels of total TAX1BP1 protein.
靶标信息
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Tax1 (human T-cell leukemia virus type I) binding protein 1; Tax1-binding protein 1; TRAF6-binding protein
基因别名: CALCOCO3; PRO0105; T6BP; TAX1BP1; TXBP151
UniProt ID: (Human) Q86VP1
Entrez Gene ID: (Human) 8887
