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产品信息
PA5-50169
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:3,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthesized peptide derived from Internal of human TAZ. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635622 |
产品详细信息
The antibody detects endogenous levels of total TAZ protein.
靶标信息
This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy, hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction. Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ27390; HGNC:11577; OTTHUMP00000061673; Protein G4.5; Tafazzin; Taz; XX-FW83563B9.3
基因别名: BTHS; CMD3A; EFE; EFE2; G4.5; LVNCX; TAFAZZIN; TAZ; Taz1
UniProt ID: (Human) Q16635
Entrez Gene ID: (Human) 6901
分子生物学功能:
acyltransferase
muscle contraction
heart development
skeletal muscle tissue development
hemopoiesis
cardiolipin biosynthetic process
mitochondrial respiratory chain complex I assembly
cardiolipin acyl-chain remodeling
cristae formation
mitochondrial ATP synthesis coupled electron transport
cardiac muscle tissue development
cardiac muscle contraction
