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Invitrogen
TBC1D2 Polyclonal Antibody
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TBC1D2 Antibody (PA5-104176) in ICC/IF
Immunofluorescent analysis of TBC1D2 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and TBC1D2 polyclonal antibody (Product # PA5-104176) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-104176
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TBC1D2(Accession Q9BYX2), corresponding to amino acid residues R62-E112.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total TBC1D2.
靶标信息
Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Armus; BC1D2; PARIS-1; Prostate antigen recognized and identified by SEREX 1; TBC1 domain family member 2A; TBC1 domain family, member 2; TBC1 domain family, member 2A
基因别名: PARIS-1; PARIS1; PP8997; TBC1D2; TBC1D2A
UniProt ID: (Human) Q9BYX2
Entrez Gene ID: (Human) 55357, (Rat) 313234
