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Invitrogen
TBPL1 Polyclonal Antibody
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产品信息
PA1-31760
产品规格
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence QIYPFVFESRKEIL, from C Terminus of the protein sequence according to NP_004856.
偶联物
形式
Liquid
浓度
0.5 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA1-31760 detects TBP like protein TLP from human samples.
PA1-31760 has been successfully used in Western blot applications.
The PA1-31760 immunogen is: Peptide with sequence QIYPFVFESRKEIL, from C Terminus of the protein sequence according to NP_004856.
靶标信息
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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