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Invitrogen
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PA1-1061 detects human and mouse TC10 protein in transfected cell samples and endogenous levels in tissue extracts. PA1-1061 is specific for isotype TC10a and demonstrates slight cross-reactivity with TC10b.
PA1-1061 has successfully been used in immunoprecipitation and Western blot procedures. By Western blot, this antibody detects an ~24 kDa protein representing TC10 in transfected COS cells and a non-specific, unidentified band at ~50 kDa.
The PA1-1061 immunogen is a synthetic peptide corresponding D(136) P K T L A R L N D M K E K P I C(152) from human TC10. This peptide (Cat. # PEP-219) is available for use in neutralization and control experiments.
TC10 is a member of the RAS superfamily of small GTP-binding proteins (see HRAS, MIM 190020) involved in insulin-stimulated glucose uptake.
仅用于科研。不用于诊断过程。未经明确授权不得转售。