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Proteintech
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Immunogen sequence: MGQEEELLR IAKKLEKMVA RKNTEGALDL LKKLHSCQMS IQLLQTTRIG VAVNGVRKHC SDKEVVSLAK VLIKNWKRLL DSPGPPKGEK GEEREKAKKK EKGLECSDWK PEAGLSPPRK KREDPKTRRD SVDSKSSASS SPKRPSVERS NSSKSKAESP KTPSSPLTPT FASSMCLLAP CYLTGDSVRD KCVEMLSAAL KADDDYKDYG VNCDKMASEI EDHIYQELKS TDMKYRNRVR SRISNLKDPR NPGLRRNVLS GAISAGLIAK MTAEEMASDE LRELRNAMTQ EAIREHQMAK TGGTTTDLFQ CSKCKKKNCT YNQVQTRSAD EPMTTFVLCN ECGNRWKFC (1-348 aa encoded by BC041613 )
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: rhabdomyosarcoma antigen MU-RMS-40.22; transcription elongation factor A (SII), 3; Transcription elongation factor A protein 3; Transcription elongation factor S-II protein 3; Transcription elongation factor TFIIS.h
基因别名: TCEA3; TFIIS; TFIIS.H; TFIISH
UniProt ID: (Human) O75764
Entrez Gene ID: (Human) 6920