应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:500-1:3,000 | - |
免疫组化(石蜡) (IHC (P)) |
1:50-1:100 | - |
产品规格 | |
---|---|
种属反应 |
Human, Mouse, Non-human primate, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthetic peptide derived from the internal region of human CCT6A |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2556066 |
The protein TCP-1 (t complex polypeptide 1) is a subunit of the heterooligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species, TCP-1 alpha, beta, gamma, delta, epsilon, zeta, eta and theta, each encoded by a different gene. Two zeta subunits have been described: TCP-1 zeta (also designated TCP-1 zeta1) and TCP-1 zeta2. TCP-1 subunits are proposed to have independent functions in folding its in vivo substrates, the actins and tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: acute morphine dependence related protein 2; Acute morphine dependence-related protein 2; amino acid transport defect-complementing; CCT zeta-1; CCT zeta1; CCT- zeta-1; CCT- zeta1; CCT-zeta-1; chaperonin containing T-complex subunit 6; chaperonin containing TCP-1; chaperonin containing TCP1, subunit 6A (zeta 1); chaperonin subunit 6a (zeta); histidine transp; histidine transport regulator 3; HTR3; T-complex protein 1 subunit zeta; T-complex protein 1, zeta subunit; TCP 1 zeta; TCP-1- zeta; TCP-1-zeta; TCP1 zeta; TCP1- zeta; Tcp20
基因别名: CCT-zeta; CCT-zeta-1; CCT6; CCT6A; CCTZ; Cctz-1; Cctz1; HTR3; MoDP-2; TCP-1-zeta; TCP20; TCPZ; TTCP20
UniProt ID: (Human) P40227, (Mouse) P80317
Entrez Gene ID: (Human) 908, (Mouse) 12466, (Rat) 288620
分子生物学功能:
chaperonin