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TCR1151 targets TCR Beta F1 in FACS, FISH, IHC, IHC(P), IP, and WB applications and shows reactivity with Human samples.
The TCR1151 immunogen is human TCR β chain constant region.
TCR1151 detects TCR Beta F1 which has a predicted molecular weight of approximately 13 kDa.
The T Cell Receptor alpha beta (TCRab) is a heterodimeric membrane receptor that consists of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 proteins. TCRab participates in the activation of T-cells in response to an antigen presented in the context of MHC. Engagement of the TCRab initiates signaling cascades that ultimately result in cellular proliferation, differentiation, cytokine production, and/or activation-induced cell death. These signaling cascades regulate T-cell development, homeostasis, activation, acquisition of effector functions and apoptosis. Cells expressing TCRab constitute the vast majority of T cells in both human and mouse.
仅用于科研。不用于诊断过程。未经明确授权不得转售。