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Invitrogen
TEC Polyclonal Antibody
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TEC Antibody (PA5-76124) in IHC (P)
Immunohistochemistry analysis of TEC in paraffin-embedded mouse spleen. Samples were incubated with TEC polyclonal antibody (Product # PA5-76124) using a dilution of 1:100. Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
产品信息
PA5-76124
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein of human TEC.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
TEC is a non-receptor protein-tyrosine kinase containing a pleckstrin homology domain and is highly expressed in many hematopoietic cell lines. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cytoplasmic tyrosine kinase, Dscr28C related; MGC126760; MGC126762; Tyrosine-protein kinase Tec
基因别名: PSCTK4; TEC
UniProt ID: (Human) P42680, (Mouse) P24604
Entrez Gene ID: (Human) 7006, (Rat) 84492, (Mouse) 21682
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding
phospholipid binding
metal ion binding
protein tyrosine kinase activity
nucleotide binding
protein kinase activity
lipid binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
adaptive immune response
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
integrin-mediated signaling pathway
regulation of platelet activation
peptidyl-tyrosine phosphorylation
cell differentiation
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
Fc-epsilon receptor signaling pathway
regulation of cell proliferation
tissue regeneration
innate immune response
positive regulation of peptidyl-tyrosine phosphorylation
B cell receptor signaling pathway
T cell receptor signaling pathway
immune system process
phosphorylation
