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Invitrogen
TEC Polyclonal Antibody
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产品信息
PA5-80101
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human Tec (612-631aa FEDLLRTIDELVECEETFGR).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.01mg sodium azide, 0.01mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human HEL whole cell, rat kidney tissue. IHC: Human Intestinal Cancer Tissue, Rat Liver Tissue.
靶标信息
TEC is a non-receptor protein-tyrosine kinase containing a pleckstrin homology domain and is highly expressed in many hematopoietic cell lines. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cytoplasmic tyrosine kinase, Dscr28C related; MGC126760; MGC126762; Tyrosine-protein kinase Tec
基因别名: PSCTK4; TEC
UniProt ID: (Human) P42680
Entrez Gene ID: (Human) 7006, (Rat) 84492
adaptive immune response
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
integrin-mediated signaling pathway
regulation of platelet activation
peptidyl-tyrosine phosphorylation
cell differentiation
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
Fc-epsilon receptor signaling pathway
regulation of cell proliferation
tissue regeneration
innate immune response
positive regulation of peptidyl-tyrosine phosphorylation
B cell receptor signaling pathway
T cell receptor signaling pathway
