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Invitrogen
TET1 Polyclonal Antibody
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TET1 Antibody (PA5-32212) in ICC/IF
TET1 Polyclonal Antibody detects TET1 protein at nucleus by immunofluorescent analysis. Sample: HepG2 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: TET1 protein stained by TET1 Polyclonal Antibody (Product # PA5-32212) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-32212
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 218 of Human Tet1
偶联物
形式
Liquid
浓度
1.0 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PA5-32212 targets TET1 in WB, ICC and IF applications and shows reactivity with mouse samples.
The PA5-32212 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 218 of Human Tet1.
靶标信息
Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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