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Invitrogen
TET1 Monoclonal Antibody (GT465)
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TET1 Antibody (MA5-31500) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of TET1 was performed in Mock and transfected 293T cells fixed in 4% paraformaldehyde at RT for 15 min. Green: TET1 Monoclonal Antibody (GT465) (Product # MA5-31500) diluted at 1:1000. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
产品信息
MA5-31500
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
GT465
抗原
Recombinant protein encompassing a sequence within the center region of human TET1.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Keep as concentrated solution.
Positive Control: NT2D1, NT2D1 nuclear extract, DDDDK-human TET1-transfected 293T, M10.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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