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产品信息
MA5-35365
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4H2M9
抗原
A synthetic peptide corresponding to amino acids 100-200 of human TFAM.
偶联物
Unconjugated
形式
Liquid
浓度
0.20 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2849266
靶标信息
TMEM192 is a widely expressed, four transmembrane protein that localizes to late endosomal/lysosomal membranes. This localization is mediated by two dileucine motifs present at the amino-terminus of TMEM192. A cysteine residue near the carboxy residue is responsible for disulfide bond formation in TMEM192 homodimers. Little is known about the function of this protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Mitochondrial transcription factor 1; mitochondrial transcription factor A; MtTF1; mtTFA; TCF-6; Testis-specific high mobility group protein; testis-specific HMG-box protein m-tsHMG; Transcription factor 6; transcription factor 6-like 1; Transcription factor 6-like 2; transcription factor 6-like 2 (mitochondrial transcription factor); transcription factor 6-like 3; Transcription factor A, mitochondrial; TS-HMG
基因别名: AI661103; Hmgts; MTTF1; MTTFA; TCF6; TCF6L1; TCF6L2; TCF6L3; TFAM; tsHMG
UniProt ID: (Human) Q00059, (Rat) Q91ZW1, (Mouse) P40630
Entrez Gene ID: (Human) 7019, (Rat) 83474, (Mouse) 21780
mitochondrial DNA replication
chromatin remodeling
regulation of transcription, DNA-templated
transcription from mitochondrial promoter
transcription initiation from mitochondrial promoter
mitochondrial respiratory chain complex assembly
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
DNA-dependent DNA replication
regulation of transcription from RNA polymerase I promoter
transcription from RNA polymerase II promoter
mitochondrion organization
transcription, DNA-templated
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription coactivator binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
DNA binding, bending
heat shock protein binding
poly(A) RNA binding
mitochondrial light strand promoter sense binding
DNA binding
